06 Exercise and depression

" Mens sana in corpore sano"
(A sound mind in a sound body)


  1. Worldwide, 350 million people suffer from depression.
  2. Common symptoms include a depressed mood, and feelings of sadness, fatigue, sleep disruption, changes in appetite and body weight, reduced interest in life events, hopelessness, and suicide. 
  3. Major risk factors include female gender, physical inactivity, family history, stress social isolation and a chronic health condition.  
  4. The greater involvement in regular exercise, the less is the risk for clinical depression. 
  5. Exercise is an all-natural treatment to fight depression
  6. Regular exercise can boost your mood if you have depression, and it's especially useful for people with mild to moderate depression.
  7. Exercising starts a biological cascade of events that results in many health benefits, such as protecting against heart disease and diabetes, improving sleep, and lowering blood pressure. High-intensity exercise releases the body's feel-good chemicals called endorphins, resulting in the "runner's high" that joggers report.
  8. Sustained low-intensity exercise over time, spurs the release of proteins called neurotrophic or growth factors, which cause nerve cells to grow and make new connections. The improvement in brain function makes one feel better.
  9. Exercise works by releasing feel-good endorphins, natural cannabis-like brain chemicals (endogenous cannabinoids) and other natural brain chemicals that can enhance sense of well-being
  10. Just two aerobic exercise sessions per week, of 20 to 30 minutes, can dramatically reduce depression and tension scores in both men and women after the 12 week intervention. 
  11. Physical exercise programme during pregnancy decreases perinatal depression risk - http://dx.doi.org/10.1136/bjsports-2017-098926
  12. In people who are depressed, neuroscientists have noticed that the hippocampus in the brain—the region that helps regulate mood—is smaller. Exercise supports nerve cell growth in the hippocampus, improving nerve cell connections, which helps relieve depression
  13. Exercise augmentation to pharmacotherapy is feasible for depressed younger and older adults and may have neural benefits in a core brain region implicated in depression.  https://doi.org/10.1016/j.jagp.2019.01.012

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